Gravois Park is one of St. Louis's densest neighborhoods, and has one of the strongest street grids I've ever seen. Unfortunately, over the past several decades, residents have arbitrarily requested that their streets be turned one-way. The result is shown below: a frustratingly damaged grid that has become hard to navigate for anyone unfamiliar with it. Additionally, motorists have take to speeding down many of the streets, making the streets less safe for pedestrians.
Draw your own conclusions from this, but I think it's hard to argue that this is the optimal street design. Fortunately, the Ward's new alderwoman has committed to reevaluating the street grid, and hopefully we'll see a more navigable neighborhood in the near future.